Abstract: Rodent behavioral testing paradigms in touchscreen operant chambers have successfully provided insight into the neural mechanisms underlying various cognitive domains in healthy and disease models. Touchscreen testing has previously required food restriction to sufficiently motivate rodents to complete behavioral tests, limiting the use of interventions,...
Abstract The retrosplenial cortex (RSC) is a hub of diverse afferent and efferent projections thought to be involved in associative learning. RSC shows early pathology in mild cognitive impairment (MCI) and Alzheimer’s disease (AD), which impairs associative learning. To understand and develop therapies for diseases such...
https://www.youtube.com/watch?v=Xz2XM5l8l-M Daring to Ask is a series that profiles Canada Research Chairs and Endowed Research Chairs at Schulich Medicine & Dentistry. These researchers are advancing knowledge in their respective fields, asking and answering questions that challenge that status quo and seeking to improve patient care. It...