Author: Tyler Dexter

Abstract Working memory is a fundamental cognitive process for decision-making and is a hallmark impairment in a variety of neuropsychiatric and neurodegenerative diseases. Spatial working memory paradigms are a valuable tool to assess these processes in rodents and dissect the neurobiology underlying working memory. The trial...

Translating results from pre-clinical animal studies to successful human clinical trials in neurodegenerative and neuropsychiatric disease presents a significant challenge. While this issue is clearly multifaceted, the lack of reproducibility and poor translational validity of many paradigms used to assess cognition in animal models are...

Poster submitted to the 2nd International Touchscreen Symposium 2020 Tyler D. Dexter 1,2, Daniel Palmer3, Amy C. Reichelt 3,4, Lisa M. Saksida 1,3,4 Tim J. Bussey 1,3,4 1 Schulich School of Medicine & Dentistry, Western University, London, ON 2 Neuroscience Program, Schulich School of Medicine & Dentistry, Western University, London,...

Presented at the Canadian Association for Neuroscience (CAN) meeting in Toronto, Ontario. 2019. Abstract: Attention is the cognitive processing that facilitates the ability to target and attend to relevant environmental stimuli, while filtering out irrelevant or distracting stimuli. Control over selective attention is theorized to be dependent...

Presented at the Southern Ontario Neuroscience Association (SONA) 2018 meeting in Guelph, Ontario. Also presented at the London Health Research Day 2018 in London, Ontario. Abstract: Executive functions encompass an assortment of mental processes that collectively enable individuals to organize, plan, and execute goal-directed behaviors. Control over...

Presented at the Physiology and Pharmacology Research Day 2018 at Western University in London, Ontario. Abstract: Attention is information processing that facilitates the ability to continuously attend to relevant environmental stimuli, while ignoring irrelevant or distracting stimuli. Control over selective attention is a central component of executing...

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