Author: Laura Lopez-Cruz

Abstract Effort-based decision-making is impaired in multiple psychopathologies leading to significant impacts on the daily life of patients. Preclinical studies of this important transdiagnostic symptom in rodents are hampered, however, by limitations present in currently available decision-making tests, including the presence of delayed reinforcement and off-target...

Abstract Despite considerable advances in both in silico and in vitro approaches, in vivo studies that involve animal model systems remain necessary in many research disciplines. Neuroscience is one such area, with studies often requiring access to a complete nervous system capable of dynamically selecting between...

Abstract Touchscreen-based assays are now widely used to study various cognitive domains in laboratory rodents. Recently, the use of this approach in assessing motivation and affective state has been proposed and new touchscreen tasks sensitive to these constructs are currently in development. In the present work, the...

Development and optimization of a touchscreen-based effort discounting task for evaluation of motivation in mice: effect of dopaminergic drugs *Poster presented at the European Behavioural Pharmacological Society (EBPS) (Crete, 2017). Abstract The rodent touchscreen apparatus has been widely used to examine rodent cognition and has recently been proposed as...

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